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Anti‐ Schistosoma mansoni effects of essential oils and their components
Author(s) -
Islam Muhammad Torequl,
Martorell Miquel,
Salehi Bahare,
Setzer William N.,
SharifiRad Javad
Publication year - 2020
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.6643
Subject(s) - schistosoma mansoni , antiprotozoal , praziquantel , antiparasitic , schistosomiasis , antimicrobial , schistosoma , essential oil , biology , antiparasitic agent , traditional medicine , in vivo , pharmacology , microbiology and biotechnology , in vitro , immunology , medicine , helminths , food science , biochemistry , pathology
Schistosoma mansoni is endemic in 55 countries around the world. S . mansoni is a water‐borne parasite of humans belonging to the group of blood flukes. Generally, schistosomiasis is treated with praziquantel, which results in frequent treatment failures and reinfections. Essential oils have diverse biological effects, including antimicrobial, antiprotozoal and antiparasitic. This review aimed at summarizing available in vitro, in vivo and clinical trials showing evidence and mechanisms of actions of essential oils and their derivatives acting against S . mansoni . The findings suggest that a number of essential oils and/or their components act against S . mansoni . Essential oils and/or their derivatives may be one of the potential sources of antischistosomal drugs.