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Stem Cell Therapy: Curcumin Does the Trick
Author(s) -
Sharifi Simin,
Zununi Vahed Sepideh,
Ahmadian Elham,
Maleki Dizaj Solmaz,
Abedi Atefeh,
Hosseiniyan Khatibi Seyed Mahdi,
Samiei Mohammad
Publication year - 2019
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.6482
Subject(s) - curcumin , stem cell , regeneration (biology) , phytochemical , pharmacology , polyphenol , wound healing , traditional medicine , antioxidant , chemistry , medicine , biology , microbiology and biotechnology , biochemistry , immunology
Curcumin is a dietary polyphenol and a bioactive phytochemical agent that possesses anti‐inflammatory, antioxidant, anticancer, and chemopreventive properties. Some of the predominant activities of stem cells include regeneration of identical cells and the ability to maintain the proliferation and multipotentiality. However, these cells could be stimulated to differentiate into specific cell types. Curcumin protects some stem cells from toxicity and can stimulate proliferation and differentiation of stem cells. In the present review, we summarize the antioxidant, stemness activity, antiaging, and neuroprotective as well as wound healing and regenerative effects of curcumin.