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Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed)
Author(s) -
Schepetkin Igor A.,
Ramstead Andrew G.,
Kirpotina Liliya N.,
Voyich Jovanka M.,
Jutila Mark A.,
Quinn Mark T.
Publication year - 2016
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.5648
Subject(s) - polyphenol , traditional medicine , antioxidant , onagraceae , biological activity , folk medicine , phytotherapy , pharmacognosy , biology , botany , chemistry , medicine , biochemistry , in vitro , alternative medicine , pathology
Epilobium angustifolium is a medicinal plant used around the world in traditional medicine for the treatment of many disorders and ailments. Experimental studies have demonstrated that Epilobium extracts possess a broad range of pharmacological and therapeutic effects, including antioxidant, anti‐proliferative, anti‐inflammatory, antibacterial, and anti‐aging properties. Flavonoids and ellagitannins, such as oenothein B, are among the compounds considered to be the primary biologically active components in Epilobium extracts. In this review, we focus on the biological properties and the potential clinical usefulness of oenothein B, flavonoids, and other polyphenols derived from E. angustifolium . Understanding the biochemical properties and therapeutic effects of polyphenols present in E. angustifolium extracts will benefit further development of therapeutic treatments from this plant. Copyright © 2016 John Wiley & Sons, Ltd.