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Scope of Hydrolysable Tannins as Possible Antimicrobial Agent
Author(s) -
Ekambaram Sanmuga Priya,
Perumal Senthamil Selvan,
Balakrishnan Ajay
Publication year - 2016
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.5616
Subject(s) - antimicrobial , gallic acid , ellagic acid , chemistry , ellagitannin , scope (computer science) , organic chemistry , polyphenol , antioxidant , computer science , programming language
Hydrolysable tannins (HTs) are secondary metabolites from plants, which are roughly classified into gallotannins and ellagitannins having gallic acid and ellagic acid residues respectively attached to the hydroxyl group of glucose by ester linkage. The presence of hexahydroxydiphenoyl and nonahydroxyterphenoyl moieties is considered to render antimicrobial property to HTs. HTs also show considerable synergy with antibiotics. Nevertheless, they have low pharmacokinetic property. The present review presents the scope of HTs as future antimicrobial agent. Copyright © 2016 John Wiley & Sons, Ltd.