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Effects of Ilex latifolia and Camellia sinensis on Cholesterol and Circulating Immune Complexes in Rats Fed with a High‐Cholesterol Diet
Author(s) -
Luo XianYang,
Li NaNa,
Liang YueRong
Publication year - 2013
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.4693
Subject(s) - cholesterol , camellia sinensis , immune system , biology , high density lipoprotein , body weight , endocrinology , lipoprotein , medicine , traditional medicine , botany , immunology
Hypercholesterolaemia is one of the risk factors for atherosclerosis and subsequent cardiovascular disease. Here, we investigated the effects of dietary supplementation with Ilex latifolia or green tea ( Camellia sinensis ) on the levels of plasma total cholesterol, high‐density lipoprotein cholesterol and circulating immune complexes in Sprague Dawley rats fed with a high‐cholesterol diet. We demonstrated that daily administration by gavage of I. latifolia or C. sinensis at doses of 1.0 or 2.0 g/kg body weight for 30 days resulted in a significant decrease in plasma total cholesterol levels and circulating immune complexes and an increase in high‐density lipoprotein cholesterol in rats fed with a high‐cholesterol diet compared with levels in the high‐cholesterol diet control group. C. sinensis was more effective than I. latifolia . I. latifolia and C. sinensis could be used as food supplements to protect against the development of hypercholesterolaemia. Copyright © 2012 John Wiley & Sons, Ltd.