Biological Activities of Indian Celery,  Seseli diffusum  (Roxb. ex Sm.) Sant. & Wagh | Zendy

Abbaskhan Ahmed | Zendy; Choudhary Muhammed Iqbal | Zendy; Ghayur Mohammed Nabeel | Zendy; Parween Zeba | Zendy; Shaheen Farzana | Zendy; Gilani AnwarulHassan | Zendy; Maruyama Takuro | Zendy; Iqbal Kiran | Zendy; Tsuda Yoshisuke | Zendy

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Biological Activities of Indian Celery, Seseli diffusum (Roxb. ex Sm.) Sant. & Wagh

Author(s) -

Abbaskhan Ahmed,

Choudhary Muhammed Iqbal,

Ghayur Mohammed Nabeel,

Parween Zeba,

Shaheen Farzana,

Gilani AnwarulHassan,

Maruyama Takuro,

Iqbal Kiran,

Tsuda Yoshisuke

Publication year - 2012

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.3600

Subject(s) - antispasmodic , traditional medicine , antioxidant , yeast , pharmacognosy , folk medicine , ether , cytotoxicity , biological activity , chemistry , medicine , biochemistry , in vitro , organic chemistry

In continuation of our work on Indian celery ( Seseli diffusum (Roxb. ex Sm.) Santapau & Wagh; Umbelliferae), the fractionation of the 80% MeOH–H 2 O extract of the seeds was performed to identify the principles responsible for its folk use as an antispasmodic and diuretic. Several compounds were isolated as active components: seselin (1) and anthriscinol methyl ether (4) showed a selective cytotoxicity to some yeast strains. Compound 1 also showed spasmolytic activity. On the other hand, isopimpinellin (3) and isorutarin (5) exhibited a spasmogenic effect on the smooth muscle preparations. Compound 5 was also found to have antioxidant activity. Among them, compound 4 was isolated for the first time from this plant. Copyright © 2011 John Wiley & Sons, Ltd.

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