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Photoprotective Effects of Topical Formulations Containing a Combination of Ginkgo biloba and Green Tea Extracts
Author(s) -
Belo Susi Elaine Dal,
Gaspar Lorena Rigo,
Campos Patrícia Maria Berardo Gonçalves Maia
Publication year - 2011
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.3507
Subject(s) - ginkgo biloba , transepidermal water loss , hairless , sunburn , erythema , ginkgoales , photoprotection , chemistry , dermatology , traditional medicine , pharmacology , medicine , biochemistry , stratum corneum , pharmacognosy , biological activity , in vitro , photosynthesis , pathology
The beneficial photoprotective effects of topical formulations containing combined extracts of Ginkgo biloba (GB) and green tea (GT) have not been investigated. The present study aims to assess the photoprotective effects of topical formulations containing GB and GT combined or not by applications on the dorsal skin of hairless mice prior to UVA/B irradiation. After 20 h, skin barrier damage (TEWL), erythema, histological alterations and sunburn cell formation were evaluated. The results showed that only extract supplemented formulations protected the skin against the UV‐induced damage. Formulations containing GB provided total protection of the skin barrier function avoiding UV radiation damage such as TEWL and erythema and were more effective than those containing GT. However, it is suggested that formulations containing combined GB and GT may provide substantial photoprotective effects since different aspects of skin damage were influenced by each extract. Copyright © 2011 John Wiley & Sons, Ltd.