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Individual and combined effects of foods on helicobacter pylori growth
Author(s) -
Keenan Jacqueline I.,
Salm Nina,
Hampton Mark B.,
Wallace Alison J.
Publication year - 2010
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.3167
Subject(s) - helicobacter pylori , nutraceutical , food science , bacteria , antibiotics , antimicrobial , biology , medicine , microbiology and biotechnology , genetics
Eradication of H. pylori can reduce the risk of non‐cardia gastric cancer developing in infected humans. Thus, the consumption of foods that inhibit the growth of these bacteria may provide an alternative to current therapies that include antibiotics, proton pump inhibitors and/or bismuth salts. This study describes a simple broth dilution assay developed to screen a range of foods for their individual and combined effects on H. pylori growth. It was found that foods with measurable anti‐ H. pylori activity have an effect greater in combination than the sum of foods tested singly, and that this was most noticeable with a combination of broccoli sprouts and blackcurrant oil. The results suggest that food synergy should be considered in any nutraceutical approach to H. pylori infection. Copyright © 2010 John Wiley & Sons, Ltd.