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Cytotoxic guaianolide from Anthemis segetalis (Asteraceae)
Author(s) -
Vučković Ivan,
Vujisić Ljubodrag,
Stešević Danijela,
Radulović Siniša,
Lazić Milan,
Milosavljević Slobodan
Publication year - 2010
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2916
Subject(s) - asteraceae , traditional medicine , pharmacognosy , chemistry , medicine , biology , botany , biological activity , in vitro , biochemistry
Two epimeric guaianolides were isolated from the aerial parts of Anthemis segetalis . These compounds have not been detected in any Anthemis species so far. One of them was tested for cytotoxicity against human cervical cancer (HeLa) and murine melanoma (B16) cell lines showing appreciable activity. Copyright © 2009 John Wiley & Sons, Ltd.