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Effect of CYSTUS052 ® and green tea on subjective symptoms in patients with infection of the upper respiratory tract
Author(s) -
Kalus Ulrich,
Kiesewetter Holger,
Radtke Hartmut
Publication year - 2010
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2876
Subject(s) - respiratory tract , medicine , respiratory tract infections , respiratory system , upper respiratory tract infection , traditional medicine
Examples of medicinal herbs that have been perpetuated along several generations based simply on a folk tradition are Cistus and green tea. The principal active constituents of the genus Cistus and green tea are polyphenolic compounds. Polyphenols exhibit a wide range of antibacterial, antifungal and antiinflammatory effects. The present work aimed to investigate the clinical effect of a Cistus extract (CYSTUS052 ® ) in comparison with green tea on 300 patients with infections of the upper respiratory tract. Due to the lack of clinical study data on their efficacy in patients, this is a report of the findings of our study on the clinical efficacy of CYSTUS052 ® in patients with the upper respiratory tract infections (URTIs). This study observed a total of 300 patients (277 completers) treated with CYSTUS052 ® given in lozenges compared with treatment with an extract of green tea. The patients scored the subjective severity of target symptoms using a predefined scale. The score of subjective symptoms decreased over the course of treatment with CYSTUS052 ® , whereas treatment with green tea resulted in a less significant decrease of symptoms. CYSTUS052 ® therefore proved to be an effective adjuvant for the treatment of respiratory infections. Copyright © 2009 John Wiley & Sons, Ltd.