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The effect of Echinacea purpurea (L.) Moench extract on experimental prostate hyperplasia
Author(s) -
Skaudickas D.,
Kondrotas A. J.,
Kevelaitis E.,
Venskutonis P. R.
Publication year - 2009
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2805
Subject(s) - hyperplasia , prostate , prostate gland , medicine , echinacea (animal) , urology , traditional medicine , endocrinology , cancer
The aim of this study was to examine the effect of purple coneflower ( Echinacea purpurea L. Moench) on the prostate gland of rats using an experimental model of benign prostate hyperplasia (BPH). The animals were administered 50 mg/kg of extract preparation for 4 and 8 weeks and the prostate mass and structural degenerative changes were evaluated in the course of the experiment. The administration of E. purpurea extract to rats with hyperplasia for 4 and 8 weeks gradually and significantly reduced the prostate mass and reversed the degenerative changes in the structure of the prostate gland. The present investigation suggests extract of purple coneflower prevents the development of BPH. Copyright © 2009 John Wiley & Sons, Ltd.