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Phenolic alkaloids as a new class of antioxidants in Portulaca oleracea
Author(s) -
Yang Zijuan,
Liu Cejia,
Xiang Lan,
Zheng Yinan
Publication year - 2009
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2742
Subject(s) - caffeic acid , portulaca , dpph , antioxidant , chemistry , lipid peroxidation , ascorbic acid , malondialdehyde , hydrogen peroxide , traditional medicine , biochemistry , food science , medicine
Antioxidant activities of three phenolic alkaloids, i.e., oleracein A (OA), oleracein B (OB) and oleracein E (OE), isolated from Portulaca oleracea were determined, based on scavenging activity against 1,1‐diphenyl‐ 2‐picryl‐hydrazyl (DPPH) radical and inhibitory effect on hydrogen peroxide‐induced lipid peroxidation in rat brain homogenates. The DPPH radical scavenging activities of these phenolic alkaloids were lower than caffeic acid but higher than ascorbic acid and α ‐tocopherol, being in the following order: OB > OA > OE. OE was most potent in preventing formation of malondialdehyde (MDA) with an EC 50 value of 73.13 µM, close to that of caffeic acid (72.09 µM). It was demonstrated that phenolic alkaloids served as a new class of antioxidant agents in this plant. Copyright © 2009 John Wiley & Sons, Ltd.