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Thyroid hormone enhancing activity of the fruits of Juglans regia L. in mice
Author(s) -
Öztürk Y.,
Aydin S.,
Arslan R.,
Baser K. H. C.,
KurtarÖztürk N.
Publication year - 1994
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650080512
Subject(s) - thyroid , hormone , medicine , endocrine system , traditional medicine , diabetes mellitus , juglans , endocrinology , biology , botany
Abstract In Turkish folk medicine, the fruits and leaves of Juglans regia L. have been widely used as a herbal remedy for the treatment of various endocrine diseases such as diabetes mellitus, anorexia, thyroid dysfunctions, etc. The effect of fruits of J. regia on the thyroid hormone levels of mice was investigated using two extracts prepared from the fruits by different methods. The acute toxicities of these two extracts in mice were assessed as well. On the basis of our findings obtained, the extracts prepared from the fruits of J. regia enhanced thyroid hormone levels, while they exerted minimal acute toxicity in mice.