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Aloctin A, an active substance of Aloe arborescens Miller as an immunomodulator
Author(s) -
Imanishi Ken'Ichi
Publication year - 1993
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650070708
Subject(s) - biological activity , in vivo , in vitro , immune system , pharmacognosy , alternative complement pathway , complement system , traditional medicine , chemistry , pharmacology , biology , immunology , medicine , biochemistry , microbiology and biotechnology
Aloctin A (Alo A), an active substance isolated from the leaves of Aloe arborescens Miller, has many biological and pharmacological activities, such as mitogenic activity for lymphocytes, binding of human α 2 ‐macroglobulin, complement activation via the alternative pathway, antiinflammatory activity, antiulcer activity and antitumour activity. In this paper, the effects of Alo A treatment in vivo and in vitro on the immune response of murine and human lymphoid cells are described.