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The antiinflammatory and liver protective effect of Tithonia diversifolia (Hemsl.) gray and Dicliptera chinensis Juss. Extracts in rats
Author(s) -
Lin ChunChing,
Lin MinLin,
Lin JerMin
Publication year - 1993
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650070409
Subject(s) - traditional medicine , tithonia , carrageenan , pharmacognosy , medicine , biology , pharmacology , botany , in vitro , biological activity , biochemistry
Abstract The antiinflammatory and liver protective effect of water extracts of Tithonia diversifolia (Hemsl.) Gray (aerial part), T. diversifolia (stem) and Dicliptera chinensis Juss. (aerial part) against paw oedema induced by carrageenan and acute hepatic damage induced by CCI 4 were determined in rats. The results indicated that treatment with a water extract of the aerial part of T. diversifolia decreased the paw oedema induced by carrageenan ( p < 0.001) and the GOT, GPT level elevation caused by CCI 4 were reduced ( p < 0.01). The pathological changes of hepatic lesions caused by CCI 4 were improved by treatment with the drug extracts mentioned above.