Stimulation of RNA polymerase activity by ginsenoside‐Rb 2  in diabetic rats | Zendy

Yokozawa Takako | Zendy; Yasui Teruhito | Zendy; Oura Hikokichi | Zendy

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Stimulation of RNA polymerase activity by ginsenoside‐Rb 2 in diabetic rats

Author(s) -

Yokozawa Takako,

Yasui Teruhito,

Oura Hikokichi

Publication year - 1993

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.2650070306

Subject(s) - rna polymerase , ginsenoside , polymerase , stimulation , rna , chemistry , streptozotocin , messenger rna , pharmacology , diabetes mellitus , microbiology and biotechnology , enzyme , biology , biochemistry , endocrinology , medicine , gene , ginseng , pathology , alternative medicine

The effect of ginsenoside‐Rb 2 on RNA polymerase activity was investigated in rats with streptozotocin‐induced diabetes. Daily intraperitoneal administration of ginsenoside‐Rb 2 for 3 or 6 days resulted in an increase of RNA polymerase I activity, as well as an increment of RNA polymerase II activity. From these results, it seems that ginsenoside‐Rb 2 promotes the synthesis of rRNA and mRNA.

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