Antispasmodic effect of  Bersama abyssinica  aqueous extract on guinea‐pig ileum | Zendy

Makonnen E. | Zendy; Hagos E. | Zendy

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Antispasmodic effect of Bersama abyssinica aqueous extract on guinea‐pig ileum

Author(s) -

Makonnen E.,

Hagos E.

Publication year - 1993

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.2650070226

Subject(s) - antispasmodic , guinea pig , traditional medicine , ileum , pharmacognosy , aqueous extract , folk medicine , chemistry , biology , biological activity , medicine , in vitro , biochemistry , endocrinology

The present study deals with the effect of one of the traditionally used Ethiopian medicinal plants, Bersama abyssinica , on gut motility. The experiment was carried out on isolated guinea‐pig ileum with a standard spasmogen, histamine, in the absence and presence of the water extract of the medicinal plant. The spasmogenic effect of histamine was found to be antagonized by the extract in a nonreversible manner, indicating that B . abyssinica has a spasmolytic activity.

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