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Study of the antioedema activity of some seaweed and sponge extracts from the mediterranean coast in mice
Author(s) -
Payá Miguel,
Ferrándiz Maria Luisa,
Sanz Maria Jesús,
Bustos Gloria,
Blasco Rafael,
Rios José Luis,
Alcaraz Maria José
Publication year - 1993
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650070213
Subject(s) - sponge , algae , brown seaweed , pharmacognosy , mediterranean climate , biology , traditional medicine , mediterranean sea , botany , ecology , biological activity , medicine , in vitro , biochemistry
Abstract Chloroform and methanol extracts of ten marine species, seven seaweeds and three sponges, have been studied for possible, antioedema activities. The extracts were administered either topically or orally on TPA‐induced mouse ear oedema and on carrageenan mouse paw oedema, respectively. The most interesting seaweed extracts were found to be from Corallina elongata, Galaxaura oblongata, Laurencia obtusa and Udotea petiolata , where both extracts of each species induced a large antioedema effect in both models employed. None of the sponges assayed demonstrated antiinflammatory effects on carrageenan mouse paw oedema, however, some extracts elicited an inhibition of the oedema developed by TPA.