Quercetin and naringenin; effects on ulcer formation and gastric secretion in rats | Zendy

Martin M. J. | Zendy; Motilva V. | Zendy; ÓN de la Lastra C. Alarc | Zendy

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Quercetin and naringenin; effects on ulcer formation and gastric secretion in rats

Author(s) -

Martin M. J.,

Motilva V.,

ÓN de la Lastra C. Alarc

Publication year - 1993

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.2650070211

Subject(s) - naringenin , quercetin , histamine , ulcer index , pepsin , gastric secretion , medicine , gastroenterology , secretion , flavonoid , pharmacology , chemistry , gastric mucosa , stomach , biochemistry , enzyme , antioxidant

The antiulcerogenic effect of two flavonoids, quercetin and naringenin, in acute gastric ulcer (cold‐restraint and pylorus‐ligated) has been investigated. In both models quercetin and naringenin presented a significant decrease in ulcer index with respect to the control group. Nevertheless, in the Shay‐ligated method no decrease in either volume, acidity or pepsin were observed, however, a significant difference was found in histamine secretion values.

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