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In vitro antibacterial activity of the volatile oil of Nigella sativa seeds against multiple drug‐resistant isolates of Shigella spp. and isolates of Vibrio cholerae and Escherichia coli
Author(s) -
Ferdous A. J.,
Islam S. N.,
Ahsan M.,
Hasan C. M.,
Ahmed Z. U.
Publication year - 1992
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650060307
Subject(s) - shigella dysenteriae , microbiology and biotechnology , shigella , vibrio cholerae , shigella sonnei , shigella boydii , shigella flexneri , tetracycline , biology , escherichia coli , vibrio parahaemolyticus , furazolidone , minimum inhibitory concentration , antimicrobial , antibiotics , bacteria , biochemistry , genetics , gene
Abstract The antibacterial activity of the volatile oil of Nigella sativa seeds was studied against 37 isolates of Shigella dysenteriae 1, Shigella flexneri, Shigella sonnei and Shigella boydii and 10 strains of Vibrio cholerae and Escherichia coli. Most of the strains were clinically resistant to ampicillin, co‐trimoxazole and tetracycline. All the strains tested showed promising sensitivity to the volatile oil. The minimum inhibitory concentration (MIC) of the volatile oil for Shigella , Vibrio and Escherichia strains tested was between 50–400 μg/mL.