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Hypertensive effect of glycosidic derivatives of hordenine isolated from Selaginella doederleinii hieron and structural analogues in rats
Author(s) -
Lin R. C.,
Peyroux J.,
Seguin E.,
Koch M.
Publication year - 1991
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650050412
Subject(s) - glycosidic bond , selaginella , traditional medicine , oral administration , chemistry , pharmacology , pharmacognosy , glycoside , medicine , biological activity , stereochemistry , biochemistry , biology , botany , enzyme , in vitro
The effect of glycosidic derivatives of hordenine isolated from Selaginella doederleinii and synthetic analogues has been studied on rat blood pressure after oral administration. A hypertensive activity was observed for the first time in this series which supports the chinese traditional medicinal use of the plant.