Premium
Studies on antiinflammatory activity of taraxasterol acetate from Echinops echinatus in rats and mice
Author(s) -
Sing Bupinder,
Ram S. N.,
Pandey V. B.,
Joshi V. K.,
Gambhir S. S.
Publication year - 1991
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650050303
Subject(s) - chemistry , carrageenan , traditional medicine , ethyl acetate , biology , biochemistry , medicine
Taraxasterol acetate, a triterpenoid found in several plant species, demonstrated antiinflammatory activity in albino rats against carrageenan, formaldehyde and adjuvant induced inflammations in doses between 10 and 100 mg/kg. Quantitative comparison of the activities of the alcoholic extract of Echinops echinatus , and taraxasterol acetate extracted from the former, suggested the presence of one or more minor, but probably more potent, antiinflammatory constitutent(s) in the original plant extract.