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Effects of short‐term capsaicin treatment on formalin and nitrogen dioxide induced changes in lipid peroxidation and antioxidant enzyme system in rat lung
Author(s) -
De Amit Krishna,
Ghosh Jagat Jiban
Publication year - 1991
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650050211
Subject(s) - capsaicin , lipid peroxidation , antioxidant , chemistry , nitrogen dioxide , lung , pharmacology , enzyme , biochemistry , medicine , organic chemistry , receptor
Exposure of rats to formalin and nitrogen dioxide vapour caused a significant increase in values of the lung wet wt/dry wt ratio (oedema formation) and lipid peroxidation. These effects were not observed in rats treated with short‐term capsaicin, either before or after exposure to the two gases. This protective action of short‐term capsaicin treatment can possibly be linked with the strengthening of the pulmonary antioxidant enzyme defence system by capsaicin.