Isolation of a saikosaponin responsible for the antiinflammatory activity of  Bupleurum gibraltaricum  lam. Root Extract | Zendy

Utrilla M. P. | Zendy; Zarzuelo A. | Zendy; Risco S. | Zendy; Ocete M. A. | Zendy; Jiménez J. | Zendy; Gamez M. J. | Zendy

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Isolation of a saikosaponin responsible for the antiinflammatory activity of Bupleurum gibraltaricum lam. Root Extract

Author(s) -

Utrilla M. P.,

Zarzuelo A.,

Risco S.,

Ocete M. A.,

Jiménez J.,

Gamez M. J.

Publication year - 1991

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.2650050113

Subject(s) - bupleurum , traditional medicine , glycoside , saponin , pharmacognosy , chemistry , isolation (microbiology) , carrageenan , botany , biological activity , biology , medicine , biochemistry , stereochemistry , in vitro , traditional chinese medicine , microbiology and biotechnology , alternative medicine , pathology

Bupleurum gibraltaricum Lam. root extract demonstrated an antiinflammatory activity against carrageenan produced plantar oedema in the rat. We have isolated a compound responsible for this activity, a glycoside of saikogenin G containing three sugars. This compound differs from saikosaponin d in that the latter contains only two sugars.

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