Premium
Isolation of a saikosaponin responsible for the antiinflammatory activity of Bupleurum gibraltaricum lam. Root Extract
Author(s) -
Utrilla M. P.,
Zarzuelo A.,
Risco S.,
Ocete M. A.,
Jiménez J.,
Gamez M. J.
Publication year - 1991
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650050113
Subject(s) - bupleurum , traditional medicine , glycoside , saponin , pharmacognosy , chemistry , isolation (microbiology) , carrageenan , botany , biological activity , biology , medicine , biochemistry , stereochemistry , in vitro , traditional chinese medicine , microbiology and biotechnology , alternative medicine , pathology
Bupleurum gibraltaricum Lam. root extract demonstrated an antiinflammatory activity against carrageenan produced plantar oedema in the rat. We have isolated a compound responsible for this activity, a glycoside of saikogenin G containing three sugars. This compound differs from saikosaponin d in that the latter contains only two sugars.