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Screening of some Somalian medicinal plants for antidiarrhoeal effects in mice
Author(s) -
Claeson Per,
Samuelsson Gunnar
Publication year - 1989
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650030505
Subject(s) - antidiarrhoeal , diarrhoeal disease , cholera , cholera toxin , traditional medicine , medicine , toxin , saline , aqueous extract , pharmacology , biology , diarrhea , microbiology and biotechnology , biochemistry , pathology , castor oil
Aqueous extracts of 10 plants, used in Somalian traditional medicine for treatment of diarrhoeal diseases, have been screened for effects against cholera toxin‐induced intestinal hypersecretion in mice. Two extracts inhibited the hypersecretion more than 50% (compared to a control group, receiving saline). For two extracts the effect did not differ significantly from the controls. The rest of the extracts showed inhibiting activities ranging from 25% to 43%.