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Effect of Terminalia arjuna extract on KCl induced contractions in the rat vas deferens
Author(s) -
Tripathi Yamini B.,
Tripathi V.,
Tripathi P.
Publication year - 1989
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650030412
Subject(s) - terminalia arjuna , vas deferens , contraction (grammar) , petroleum ether , chemistry , muscle contraction , chloride , smooth muscle , potassium , biophysics , pharmacology , traditional medicine , medicine , biology , chromatography , terminalia , organic chemistry , extraction (chemistry)
Experiments were carried out to elucidate the effects of extracts from Terminalia arjuna on potassium chloride (160 mM) induced contraction in smooth muscle. The petroleum ether extract did not exhibit a response, whereas the preincubation of tissue with the alcoholic extract inhibited contraction. Experimental approaches, described here, lead to the speculation that T. arjuna may impart its action through the modulation of Ca 2+ ions across the cellular membrane.