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Capsaicin pretreatment protects free radical induced rat lung damage on exposure to gaseous chemical lung irritants
Author(s) -
De Amit Krishna,
Ghosh Jagat Jiban
Publication year - 1989
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650030411
Subject(s) - capsaicin , lung , lipid peroxidation , chemistry , pharmacology , sulfur dioxide , nitrogen dioxide , medicine , biochemistry , antioxidant , organic chemistry , receptor
Pretreatment with capsaicin tends to normalize pulmonary lipid peroxidation changes induced by exposure to sulfur dioxide, formalin or nitrogen dioxide gases. This protective effect of capsaicin pretreatment appears to be due to the stabilization of the rat lung membrane lipid system.