Premium
The spasmolytic activity of the essential oil of Thymus baeticus boiss in rats
Author(s) -
Cruz T.,
Jiménez J.,
Zarzuelo A.,
Cabo M. M.
Publication year - 1989
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650030308
Subject(s) - essential oil , acetylcholine , duodenum , traditional medicine , ileum , chemistry , pharmacology , biology , medicine , botany , endocrinology
Gas chromatography and GC/MS studies of Thymus baeticus Boiss essential oil showed its major component to be 1,8‐cineole. The essential oil was found to present a marked spasmolytic activity in rat duodenum against acetylcholine via a non‐competitive type of inhibition. This action was not related to its major component, 1,8‐cineole.