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The antiinflammatory activity of the fractions from Eryngium billardieri in mice
Author(s) -
Yesilada Erdem,
Tanaka Shigeo,
Tabata Mamoru,
Sezik Ekrem
Publication year - 1989
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650030111
Subject(s) - carrageenan , pharmacognosy , traditional medicine , chemistry , pharmacology , folk medicine , vascular permeability , serotonin , bradykinin , apocynaceae , acetic acid , biological activity , medicine , biochemistry , in vitro , endocrinology , receptor
Eryngium billardieri Delar., used as a folk medicine in Turkey for the treatment of inflammatory diseases, was investigated for its antiinflammatory activity by various methods. Fractions obtained from the aerial parts and roots of E. billardieri were tested in mice for their effects on increased vascular permeability induced by acetic acid intraperitoneally, and serotonin, bradykinin, and carrageenan‐induced edemas. A significant antiinflammatory activity was observed only in the precipitated part of the butanol extract of the roots, which contains saponins.