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Chemical constituents of Rhamnus procumbens and pharmacological actions of emodin
Author(s) -
Dwivedi S. P. D.,
Pandey V. B.,
Shah A. H.,
Rao Y. B.
Publication year - 1988
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650020109
Subject(s) - emodin , traditional medicine , pharmacognosy , plant roots , biology , chemical constituents , chemistry , biological activity , botany , medicine , biochemistry , in vitro , chromatography
Musizin, physcon, emodin and frangulin‐A have been isolated from the whole plant of Rhamnus procumbens and their structures established by a detailed study of spectral data and also by degradation methods. Pharmacological investigations on emodin have indicated that it possesses intestinal and cardiac stimulant, CNS depressant and analgesic activities. Such activities have not earlier been reported for emodin. This is also the first report of the isolation of these chemical constituents in Rhamnus procumbensf and the second natural occurrence of musizin.