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Spasmolytic activity of Thymus membranaceus essential oil
Author(s) -
Zarzuelo A.,
Navarro C.,
Crespo M. E.,
Ocete M. A.,
Jiménez J.,
Cabo J.
Publication year - 1987
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2650010304
Subject(s) - essential oil , duodenum , acetylcholine , phenols , chemistry , biological activity , composition (language) , pharmacology , biology , traditional medicine , food science , biochemistry , medicine , in vitro , philosophy , linguistics
Abstract The spasmolytic activity of Thymus membranaceus essential oil in the duodenum isolated from rat has been investigated. The qualitative and quantitative composition of the essential oil was studied. The essential oil affects the duodenum in two ways, showing a spasmogenic action (due to 1,8‐cineole) and, on the other hand, an antagonistic non‐competitive effect against the contractions by acetylcholine (due to the phenols and hydrocarbons).