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Lipase inhibitory activity in alcohol extracts of worldwide occurring plants and propolis
Author(s) -
Möller Niels Peter,
Roos Nils,
Schrezenmeir Jürgen
Publication year - 2009
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2637
Subject(s) - propolis , lipase , triolein , ethanol , alcohol , linum , triacylglycerol lipase , inhibitory postsynaptic potential , sunflower , traditional medicine , chemistry , sunflower oil , biology , biochemistry , food science , botany , enzyme , medicine , horticulture , neuroscience
Abstract In the search for lipase inhibitory agents, 144 alcohol plant extracts and propolis were screened for pancreatic lipase activity in vitro using methods with methylresorufin and triolein as substrates. Ethanol extracts of Linum usitatissimum (oil flax) and Helianthus annuus (sunflower seeds) showed the strongest lipase inhibitory actions with ID 50 values of 1:370 and 1:166, respectively. Copyright © 2008 John Wiley & Sons, Ltd.