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Effects of cuminaldehyde on melanoma cells
Author(s) -
Nitoda Teruhiko,
Fan Maria D.,
Kubo Isao
Publication year - 2008
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2374
Subject(s) - melanin , melanoma , cell culture , cell growth , chemistry , biology , food science , traditional medicine , pharmacology , medicine , biochemistry , cancer research , genetics
Cuminaldehyde (4‐isopropylbenzaldehyde) suppressed melanin formation in cultured murine B16‐F10 melanoma cells in a dose‐dependent decrease up to 0.25 m m without affecting cell growth. Approximately 30% suppression in melanin production resulted when the cells were cultured with 0.25 m m of cuminaldehyde. This activity was not noticeable with cultured human A375 melanoma cells. Copyright © 2008 John Wiley & Sons, Ltd.
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