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In vitro and in vivo antiplasmodial activity of ‘Saye’, an herbal Remedy used in Burkina Faso traditional medicine
Author(s) -
Traoré M.,
Diallo A.,
Nikièma J. B.,
Tinto H.,
Dakuyo Z. P.,
Ouédraogo J. B.,
Guissou I. P.,
Guiguemdé T. R.
Publication year - 2008
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2308
Subject(s) - traditional medicine , rhizome , in vivo , cassia , plasmodium berghei , pharmacognosy , in vitro , plasmodium falciparum , biology , phytotherapy , pharmacology , malaria , medicine , biological activity , traditional chinese medicine , microbiology and biotechnology , immunology , biochemistry , alternative medicine , pathology
‘Saye’, a traditional medicine used in Burkina Faso, which consists of extracts of Cochlospermum planchonii (rhizome), Cassia alata (leaf) and Phyllanthus amarus (whole plant), showed a significant effect against Plasmodium falciparum and Plasmodium berghei parasites grown in vivo (IC 50 = 80.11 ± 3.40 µg/mL; ED 50 = 112.78 ± 32.32 mg/kg). In vitro the activity was lower. Copyright © 2007 John Wiley & Sons, Ltd.