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Antibacterial activity of Chamomilla recutita oil extract against Helicobacter pylori
Author(s) -
Shikov Alexander N.,
Pozharitskaya Olga N.,
Makarov Valery G.,
Kvetnaya Asya S.
Publication year - 2008
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2243
Subject(s) - essential oil , antibacterial activity , traditional medicine , helicobacter pylori , matricaria chamomilla , food science , agar dilution , minimum inhibitory concentration , chemistry , biology , antimicrobial , botany , microbiology and biotechnology , medicine , bacteria , genetics
The antibacterial activity of an oil extract of Chamomilla recutita flowers against Helicobacter pylori ( H. pylori ) was evaluated by the agar dilution method using Colombia agar with 10% sheep blood, an inoculum of McFarland 0.5 and incubation in an anaerobic atmosphere at 37 °C for 3 days. The oil extract was prepared by olive oil extraction of Chamomilla recutita flowers using rotary pulsation. The MIC 90 (minimal inhibitory concentration) and MIC 50 were 125 mg/mL and 62.5 mg/mL, respectively. It was shown that the Chamomilla recutita oil extract inhibited the production of urease by H. pylori . In addition, it was found that the morphological and fermentative properties of H. pylori were affected by application of the Chamomilla recutita oil extract. Copyright © 2007 John Wiley & Sons, Ltd.
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