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Antiobesity properties of two African plants ( Afromomum meleguetta and Spilanthes acmella ) by pancreatic lipase inhibition
Author(s) -
Ekanem A. P.,
Wang M.,
Simon J. E.,
Moreno D. A.
Publication year - 2007
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2239
Subject(s) - lipase , ethanol , pancreatic lipase , traditional medicine , in vitro , chemistry , biochemistry , botany , food science , enzyme , biology , medicine
Ethanol extracts of seeds of Afromomum meleguetta and flower buds of Splilanthes acmella presented pancreatic lipase inhibitory activities in a concentration related manner under in vitro conditions. The two plants were extracted with 70% ethanol by sonication, fractionated on silica gel and tested at concentrations in the range 0.75–2.0 mg/mL. Lipase inhibitory activities of 90% and 40% were observed in A. meleguetta and S. acmella , respectively. The two plants have potentials as candidates for weight reduction and obesity control. Copyright © 2007 John Wiley & Sons, Ltd.