Antiobesity properties of two African plants ( Afromomum meleguetta  and  Spilanthes acmella ) by pancreatic lipase inhibition | Zendy

Ekanem A. P. | Zendy; Wang M. | Zendy; Simon J. E. | Zendy; Moreno D. A. | Zendy

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Antiobesity properties of two African plants ( Afromomum meleguetta and Spilanthes acmella ) by pancreatic lipase inhibition

Author(s) -

Ekanem A. P.,

Wang M.,

Simon J. E.,

Moreno D. A.

Publication year - 2007

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.2239

Subject(s) - lipase , ethanol , pancreatic lipase , traditional medicine , in vitro , chemistry , biochemistry , botany , food science , enzyme , biology , medicine

Ethanol extracts of seeds of Afromomum meleguetta and flower buds of Splilanthes acmella presented pancreatic lipase inhibitory activities in a concentration related manner under in vitro conditions. The two plants were extracted with 70% ethanol by sonication, fractionated on silica gel and tested at concentrations in the range 0.75–2.0 mg/mL. Lipase inhibitory activities of 90% and 40% were observed in A. meleguetta and S. acmella , respectively. The two plants have potentials as candidates for weight reduction and obesity control. Copyright © 2007 John Wiley & Sons, Ltd.

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