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The effect of Echinacea purpurea , Astragalus membranaceus and Glycyrrhiza glabra on CD25 expression in humans: a pilot study
Author(s) -
Zwickey Heather,
Brush Julie,
Iacullo Carolyn M.,
Connelly Erin,
Gregory William L.,
Soumyanath Amala,
Buresh Randal
Publication year - 2007
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2207
Subject(s) - echinacea (animal) , astragalus , glycyrrhiza , traditional medicine , medicine , pharmacognosy , biology , pharmacology , in vitro , biological activity , traditional chinese medicine , biochemistry , alternative medicine , pathology
This phase 0, double‐blind, repeated within subject, randomized pilot study examined CD25 expression on T cells after ingestion of three commonly used herbs: Echinacea purpurea , Astragalus membranaceus and Glycyrrhiza glabra , administered singly and in combination. CD25 expression on T cells was significantly increased for subjects ingesting Echinacea at 24 h with notable increases in activation from Astragalus and Glycyrrhiza . CD25 expression remains elevated with daily use of Echinacea for at least 7 days. Copyright © 2007 John Wiley & Sons, Ltd.
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