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A novel cytotoxic lignan from Seseli annuum L.
Author(s) -
Vučković Ivan,
Trajković Vladimir,
Macura Slobodan,
Tešević Vele,
Janaćković Ped̄a,
Milosavljević Slobodan
Publication year - 2007
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2152
Subject(s) - lignan , coumarin , cytotoxic t cell , traditional medicine , cytotoxicity , pharmacognosy , biology , botany , chemistry , biological activity , biochemistry , medicine , in vitro
A new tetrahydrofuranoid lignan named seselinone was isolated from the aerial parts of Seseli annuum , together with three known lignans (eudesmin, magnone A and hernone) and prenylated coumarin umbelliprenin. Seselinone and eudesmin showed cytotoxic activity against C6 rat glioma cell cultures. Copyright © 2007 John Wiley & Sons, Ltd.