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Bio‐guided isolation of antioxidants from the stems of Dendrobium aurantiacum var. denneanum
Author(s) -
Yang Li,
Han Haofeng,
Nakamura Norio,
Hattori Masao,
Wang Zhengtao,
Xu Luoshan
Publication year - 2007
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2133
Subject(s) - dendrobium , dpph , fractionation , antioxidant , stereochemistry , chemistry , traditional medicine , genus , botany , organic chemistry , biology , medicine
Bio‐guided fractionation of the stems of Dendrobium aurantiacum var. denneanum using a 1,1‐diphenyl‐2‐picryl‐hydrazyl (DPPH) radical scavenging assay, led to the isolation of three 2‐glucosyloxycinnamic acid derivates, namely, cis ‐melilotoside, trans ‐melilotoside and dihydromelilotoside, respectively. Their structures were elucidated through the analysis of uni‐ and bi‐dimensional NMR, UV, IR and MS data. All these three compounds were first reported from the genus Dendrobium and exhibited potent antioxidant activities. Copyright © 2007 John Wiley & Sons, Ltd.