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Screening seeds of some Scottish plants for free radical scavenging activity
Author(s) -
Kumarasamy Yashodharan,
Byres Maureen,
Cox Philip J.,
Jaspars Marcel,
Nahar Lutfun,
Sarker Satyajit D.
Publication year - 2007
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.2129
Subject(s) - dpph , scavenging , traditional medicine , prunus , prunus cerasus , dichloromethane , botany , chemistry , antioxidant , biology , biochemistry , sour cherry , medicine , cultivar , solvent
From a consideration of ethnobotanical and taxonomic information, seeds of 45 Scottish plant species encompassing 23 different families were obtained from authentic seed suppliers. The n‐ hexane, dichloromethane (DCM) and methanol (MeOH) extracts were assessed, both qualitatively and quantitatively, for free radical scavenging activity in the DPPH assay. The MeOH extracts of 37 species exhibited low to high levels of free radical scavenging activity (RC 50 values ranging from 2.00 to 4.7 × 10 −4 mg/mL), and Alliaria petiolata , Prunus padus and Prunus spinosa were the most potent antioxidant extracts. The DCM extracts of 17 species showed similar levels of activity, and among those, Prunus padus and Prunus spinosa extracts were the most active with RC 50 values of 2.5 × 10 −4 and 5.0 × 10 −4 mg/mL, respectively. The n ‐hexane extracts were much less active than the MeOH and DCM extracts, and 17 species, with the exception of Glechoma hederacea (RC 50 = 1.94 × 10 −4 ) displayed low to moderate levels of free radical scavenging property (RC 50 values ranging from 2.00 to 8.7 × 10 −3 mg/mL). Copyright © 2007 John Wiley & Sons, Ltd.