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Acceleration of lipid degradation by sericoside of Terminalia sericea roots in Fully differentiated 3T3‐L1 cells
Author(s) -
Mochizuki Miyako,
Hasegawa Noboru
Publication year - 2006
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1999
Subject(s) - combretaceae , triglyceride , glycerol , terminalia , lipolysis , cytosol , saponin , chemistry , biochemistry , traditional medicine , biology , botany , cholesterol , adipose tissue , medicine , enzyme , alternative medicine , pathology
Sericoside is a traditional herbal saponin from Terminalia sericea (Family Combretaceae). The influence of sericoside on lipolysis was studied in fully differentiated 3T3‐L1 cells, and glycerol release into the cytosol and residual triglyceride were measured. The addition of sericoside stimulated glycerol release into the cytosol from deposited triglyceride in a dose‐ and time‐dependent manner. These data suggested that sericoside has a strong lipolytic activity. Copyright © 2006 John Wiley & Sons, Ltd.