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Inhibitory effect of polar oregano extracts on aldose reductase and soybean lipoxygenase in vitro
Author(s) -
Koukoulitsa Catherine,
Zika Chariklia,
Hadjipavlou–Litina Dimitra,
Demopoulos Vassilis J.,
Skaltsa Helen
Publication year - 2006
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1901
Subject(s) - aldose reductase , lipoxygenase , origanum , chemistry , in vitro , aldose reductase inhibitor , reductase , methanol , traditional medicine , biochemistry , enzyme , medicine , food science , organic chemistry , essential oil
The effect of methanol and aqueous methanol extract of Origanum vulgare L. ssp. hirtum on aldose reductase and soybean lipoxygenase was investigated. The results revealed a promising potential of oregano for preventing diabetes complications in the long term and an antiinflammatory efficacy by inhibiting soybean lipoxygenase. Copyright © 2006 John Wiley & Sons, Ltd.