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Leishmanicidal activity of Pycnoporus sanguineus
Author(s) -
Correa Edwin,
Cardona Diana,
Quiñones Winston,
Torres Fernando,
Franco Ana E.,
Vélez Ivan D.,
Robledo Sara,
Echeverri Fernando
Publication year - 2006
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1890
Subject(s) - amastigote , leishmania , biology , ergosterol , traditional medicine , leishmaniasis , microbiology and biotechnology , stereochemistry , chemistry , botany , medicine , parasite hosting , immunology , world wide web , computer science
In the search for antiparasite compounds from the Colombian flora, an active compound against Leishmania (Viannia) panamensis amastigotes was isolated from the fungi Pycnoporus sanguineus . The structural elucid‐ation was achieved with spectroscopic methods ( 1 H and 13 C NMR and MS). This compound was identified as ergosterol 5,8‐endoperoxide. Copyright © 2006 John Wiley & Sons, Ltd.