Screening of Thai medicinal plant extracts and their active constituents for  In Vitro  antimalarial activity | Zendy

Ichino C. | Zendy; Soonthornchareon N. | Zendy; Chuakul W. | Zendy; Kiyohara H. | Zendy; Ishiyama A. | Zendy; Sekiguchi H. | Zendy; Namatame M. | Zendy; Otoguro K. | Zendy; Omura S. | Zendy; Yamada H. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Screening of Thai medicinal plant extracts and their active constituents for In Vitro antimalarial activity

Author(s) -

Ichino C.,

Soonthornchareon N.,

Chuakul W.,

Kiyohara H.,

Ishiyama A.,

Sekiguchi H.,

Namatame M.,

Otoguro K.,

Omura S.,

Yamada H.

Publication year - 2006

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1850

Subject(s) - traditional medicine , plasmodium falciparum , medicinal plants , biology , pharmacognosy , in vitro , malaria , botany , biological activity , medicine , biochemistry , immunology

To discover antimalarial substances from plants cultivated in Thailand 80%‐EtOH extracts from selected plants were screened for in vitro antimalarial activity against the drug resistant K1 strain of Plasmodium falciparum . In total, 86 Thai medicinal plant samples representing 48 species from 35 genera in 16 families were screened and two species ( Polyalthia viridis and Goniothalamus marcanii ) were found to show notable antimalarial activity (IC 50 : 10.0 and 6.3 µg/mL). Marcanine A and 16‐hydroxycleroda‐3,13(14)Z‐dien‐15,16‐olide were identified as the respective major active constituents in P. viridis and G. marcanii , respectively. Copyright © 2006 John Wiley & Sons, Ltd.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research