Antiviral properties of ent‐labdene diterpenes of  Andrographis paniculata  nees, inhibitors of herpes simplex virus type 1 | Zendy

Wiart C. | Zendy; Kumar K. | Zendy; Yusof M. Y. | Zendy; Hamimah H. | Zendy; Fauzi Z. M. | Zendy; Sulaiman M. | Zendy

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Antiviral properties of ent‐labdene diterpenes of Andrographis paniculata nees, inhibitors of herpes simplex virus type 1

Author(s) -

Wiart C.,

Kumar K.,

Yusof M. Y.,

Hamimah H.,

Fauzi Z. M.,

Sulaiman M.

Publication year - 2005

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1765

Subject(s) - andrographis paniculata , andrographolide , herpes simplex virus , cytotoxicity , traditional medicine , virology , pharmacognosy , diterpene , virus , biology , pharmacology , chemistry , stereochemistry , medicine , biological activity , in vitro , biochemistry , alternative medicine , pathology

Andrographolide, neoandrographolide and 14‐deoxy‐11,12‐didehydroandrographolide, ent‐labdene diterpenes isolated from Andrographis paniculata showed viricidal activity against herpes simplex virus 1 (HSV‐1). None of these compounds exhibited significant cytotoxicity at viricidal concentrations. Copyright © 2005 John Wiley & Sons, Ltd.

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