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Inhibition of hepatitis B virus by an aqueous extract of Agrimonia eupatoria L.
Author(s) -
Kwon Dur Han,
Kwon Hyuk Yun,
Kim Hyun Jung,
Chang Eun Joo,
Kim Man Bae,
Yoon Seung Kew,
Song Eun Young,
Yoon Do Young,
Lee Young Hee,
Choi In Seong,
Choi Yong Kyung
Publication year - 2005
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1689
Subject(s) - hbsag , pharmacognosy , traditional medicine , inhibitory postsynaptic potential , aqueous extract , virus , biology , hepatitis b virus , botany , biological activity , chemistry , in vitro , virology , medicine , biochemistry , endocrinology
Inhibition of HBsAg release against hepatitis B virus (HBV) was investigated in an aqueous extract prepared from the aerial parts (stems and leaves) of Agrimonia eupatoria . The inhibitory effect on HBsAg secretion was footed using aqueous extracts of Agrimonia eupatoria at four different temperatures (37 °C 45 °C, 55 °C and 60 °C), and the extract prepared at 60 °C was found to have the greatest effect. The inhibitory activity of Agrimonia eupatoria extracts on HBsAg secretion varied over the growing season and was the highest at mid‐July. This inhibitory activity was also shown with the aqueous extracts of two other species of the genus Agrimonia: A. pilosa and A. coreana pilosella . These results suggest that some plants of the genus Agrimonia contain potential antiviral activity against HBV. Copyright © 2005 John Wiley & Sons, Ltd.