The hepatoprotective action of ten herbal extracts in CCl 4  intoxicated liver | Zendy

Rusu M. A. | Zendy; Tamas M. | Zendy; Puica C. | Zendy; Roman Ioana | Zendy; Sabadas Mihaela | Zendy

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The hepatoprotective action of ten herbal extracts in CCl 4 intoxicated liver

Author(s) -

Rusu M. A.,

Tamas M.,

Puica C.,

Roman Ioana,

Sabadas Mihaela

Publication year - 2005

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1625

Subject(s) - lactate dehydrogenase , traditional medicine , calendula officinalis , officinalis , succinate dehydrogenase , eosin , ccl4 , malate dehydrogenase , haematoxylin , aspartate transaminase , bilirubin , steatosis , leech , alanine transaminase , staining , biochemistry , pharmacology , biology , chemistry , enzyme , carbon tetrachloride , alkaline phosphatase , medicine , endocrinology , world wide web , organic chemistry , computer science , genetics

The effect of ten phytotherapeutic products on CCl 4 intoxicated liver in albino male Wistar rats was investigated. Biochemical parameters, including serum transaminase activity (GPT and GOT), histoenzymological measurements (lactate dehydrogenase, LDH; succinate dehydrogenase, SDH, cytochromoxidase, CyOx; Mg 2+ ‐dependent adenosine triphosphatase, ATP‐ase) and histochemical (Sudan black) and histological examinations (haematoxylin‐eosin staining) of the liver were investigated. Some positive effects such as the reduction of hepatocytolysis and steatosis, and a return to normal values of the activity of some enzymes in the following plants: Chrysanthemum balsamita , Echinacea pallida , Calendula officinalis and Corylus avelana were obtained. Copyright © 2005 John Wiley & Sons, Ltd.

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