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Yeast hydrolysate reduces body fat of dietary obese rats
Author(s) -
Kim K. M.,
Chang U. J.,
Kang D. H.,
Kim J. M.,
Choi Y. M.,
Suh H. J.
Publication year - 2004
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1582
Subject(s) - hydrolysate , medicine , endocrinology , body weight , adipose capsule of kidney , significant difference , yeast , obesity , chemistry , biology , biochemistry , kidney , hydrolysis
The purpose of this study was to assess the antiobesity effect of the yeast hydrolysate (DNF) on the body weight, body fat and plasma lipids levels of high‐fat fed rats. The weight gain of the HF (high fat diet) (162.58 ± 6.68 g) was signicantly ( p < 0.05) greater than that of DNF‐1, DNF‐2, (high fat diet with DNF of 0.5 and 1.0 g/kg body weight, respectively) and control groups (143.19 ± 7.33 g, 139.20 ± 8.36 g, 130.23 ± 8.02 g, respectively). The wet weight of the epididymal fat and the perirenal fat pads of the DNF‐1, DNF‐2 and control groups were reduced signicantly ( p < 0.05). A signicant ( p < 0.05) increase of HDL‐cholesterol level of the DNF‐2 and control groups was observed. However, there was no signicant difference between DNF‐1 and DNF‐2. It was also found that the triacylglycerol (TG) levels decreased signicantly ( p < 0.05) in the DNF‐2 group from that of the HF, but there was no signicant ( p < 0.05) difference between DNF‐1 and DNF‐2. Copyright © 2004 John Wiley & Sons, Ltd.