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Evaluation of antitussive activity of Lagerstroemia parviflora leaf extract
Author(s) -
Mazumder Avijit,
Saha B. P.,
Basu S. P.,
Mazumder Rupa,
Boominathan R.,
Devi B. Parimala,
Mandal S. C.
Publication year - 2004
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1571
Subject(s) - traditional medicine , codeine , pharmacognosy , medicine , cough reflex , pharmacology , chemistry , biological activity , reflex , anesthesia , in vitro , morphine , biochemistry
Abstract The methanol extract of the leaves of Lagerstroemia parviora Roxb was investigated for its effect on a cough model induced by sulfur dioxide gas in mice. It exhibited signicant antitussive activity when compared with the control in a dose‐dependent manner. The L. parviora extract (100, 200, 300 mg/kg) showed maximum inhibition of cough reex at 90 min after drug administration and the antitussive activity was comparable to that of codeine phosphate, a standard antitussive agent. Copyright © 2004 John Wiley & Sons, Ltd.