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In vivo and in vitro activities of the seed extract of Piper guineense Schum. and Thonn. against skin and gill monogenean parasites of goldfish ( Carassius auratus auratus )
Author(s) -
Ekanem A. P.,
Wang M.,
Simon J. E.,
Obiekezie A. I.,
Morah F.
Publication year - 2004
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1550
Subject(s) - piperaceae , piper , in vivo , biology , traditional medicine , in vitro , botany , pharmacognosy , biological activity , biochemistry , medicine , microbiology and biotechnology
Methanol extracts of the seeds of Piper guineense (Piperaceae) were active against goldsh ( Carassius auratus auratus L. Pisces Cyprinidae) monogenean parasites. The seed extract of P. guineense was administered at different concentrations (0.5–2.0 mg/L) under in vivo and in vitro conditions. There was a higher efcacy of the effects of the extracts against sh parasites under in vitro situations than under in vivo . Three major compounds (piperanine, N ‐isobutyl (E,E)‐2,4 decadienamide and Δ α , β ‐dihydrowasanine) were identied from the seed extract of Piper guineense by LC‐MS analysis. Copyright © 2004 John Wiley & Sons, Ltd.