In vivo  and  in vitro  activities of the seed extract of  Piper guineense  Schum. and Thonn. against skin and gill monogenean parasites of goldﬁsh ( Carassius auratus auratus ) | Zendy

Ekanem A. P. | Zendy; Wang M. | Zendy; Simon J. E. | Zendy; Obiekezie A. I. | Zendy; Morah F. | Zendy

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In vivo and in vitro activities of the seed extract of Piper guineense Schum. and Thonn. against skin and gill monogenean parasites of goldﬁsh ( Carassius auratus auratus )

Author(s) -

Ekanem A. P.,

Wang M.,

Simon J. E.,

Obiekezie A. I.,

Morah F.

Publication year - 2004

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1550

Subject(s) - piperaceae , piper , in vivo , biology , traditional medicine , in vitro , botany , pharmacognosy , biological activity , biochemistry , medicine , microbiology and biotechnology

Methanol extracts of the seeds of Piper guineense (Piperaceae) were active against goldsh ( Carassius auratus auratus L. Pisces Cyprinidae) monogenean parasites. The seed extract of P. guineense was administered at different concentrations (0.5–2.0 mg/L) under in vivo and in vitro conditions. There was a higher efcacy of the effects of the extracts against sh parasites under in vitro situations than under in vivo . Three major compounds (piperanine, N ‐isobutyl (E,E)‐2,4 decadienamide and Δ α , β ‐dihydrowasanine) were identied from the seed extract of Piper guineense by LC‐MS analysis. Copyright © 2004 John Wiley & Sons, Ltd.

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